Chromatrap is a unique bead-free platform for immunoprecipitation (ChIP), and they are releasing Chip sequencing kits.

Chromatrap® is offering researchers a new way of performing ChIP, effortlessly. Their goal is to enable the advancement of epigenetic research through the revolutionary bead-free system.

The new ChIP-seq kit utilizes the solid-state technology to deliver a streamlined ChIP-seq protocol from small cell numbers and low chromatin concentrations.

Chromatrap® is a unique bead-free platform for chromatin immunoprecipitation (ChIP). ChIP is carried out using a solid-state filter (vs beads floating in liquid or packed). This filter is composed of an inert porous polymer matrix with Protein-A or Protein-G on the surface and throughout the structure.

This increased surface area maximizes immunocapture of antibody-chromatin complexes from your samples. The development of chromatin immunoprecipitation, or ChIP, assays have tremendously enhanced the biological significance of the multifaceted DNA-binding proteins.

The technical team Chromatrap® are deeply involved in the development and improvement of the field. An advantage of the Chromatin Immunoprecipitation is that is easy to use, so those wishing to further the development of this powerful tool can continue examining the vast complexity of the cell’s biology.

Chromatrap® and its patented filter was highlighted by academics at Essex University and later developed in collaboration with Swansea University’s Medical School. It began with a kit designed for PCR analysis, after that the partnership inspired the development of a diverse product range offering a faster, easier and more sensitive method of chromatin immunoprecipitation.

Chromatrap is unlike other bead-based kit suppliers such as Active Motif, Diagenode, Cell Signalling Technology, Abcam, Zymo Research and Epigentik.  It is more like a novel filter-based system that overcomes the challenges often encountered through the use of beads. This can happen to first-time users.

All Chromatrap® products are manufactured at the Porvair Sciences biosciences facilities in North Wales and now sold globally.

The talented and dedicated technical team at Chromatrap continues to improve and innovate the technology and its protocols to ensure that researchers get the results they want, allowing them to focus on the more significant questions in epigenetics research.

Chromatrap offers products that have a range of features such as:

• Easy to use simple spin-column protocol
• Unrivalled low background inert filter surface
• Fast workflow high-quality data in under 5 hours
• No Sample loss sample captured and retained on the filter until elution
• Less handling errors

Also, Chromatrap’s product has a:

• High throughput capability process
• Perfectly orientated proteins
• Exceptional signal-to-noise inert filtration material
• High binding capacity optimally orientated highly ordered protein arrangement

Chromatrap®’s wide range of products which include the ChIP kits for qPCR and a variety of ChIP Validated Antibodies and Primers are essential for the success of a ChIP assay.

Chromatrap® is a brand of Porvair Sciences Ltd., and they have R&D production laboratories located within the UK. Their extensive product range not only includes ChIP kits but DNA clean up kits and other innovative products for the life science market. There is clear evidence today that Chromatrap® ChIP technology is becoming the method of choice for accurate ChIP assays.

Contact the team at Chromatrap® if you have any questions or queries, and you are unsure which kit is right for your research. You can fill in their form online at https://www.chromatrap.com/, and one of their team members will be in touch. Or why not call their sales team on (+44 (0)1978 661144) or technical support team (+44 (0) 1978 661144).

SOURCE: The News Front [Link]